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Human CD40L Receptor Protein, Fc Tag产品信息
产品编号 KMP2383
产品名称 Human CD40L Receptor Protein, Fc Tag
产品描述 The Human CD40L Receptor Protein(KMP2383) is produced in HEK293 Cells and the target gene encoding Glu21-Arg193 is expressed with a Fc tag at the C-terminus.
物种 Human
宿主 HEK293 Cells
规格 50ug, 100ug, 200ug
纯化方式 Affinity purification
内毒素水平 <1.0 EU/ug determined by the LAL method
缓冲体系 20mM PB, 150mM NaCl, pH7.4
SDS-PAGE
产品背景 CD40 is a Type I Transmembrane Glycoprotein that belongs to the TNF Receptor Superfamily. CD40 is expressed in B cells, follicular dendritic cells, dendritic cells, activated monocytes, macrophages, endothelial cells, vascular smooth muscle cells, and several tumor cell lines. The extracellular domain of CD40 is characterized by Cysteine rich repeat regions. Interaction of CD40 with its ligand(CD40L) leads to aggregation of CD40 molecules, which in turn interact with cytoplasmic components to initiate signaling pathways. Several different TRAF proteins(adaptor proteins) have been identified to serves as mediators of the signal transduction. CD40 plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation.
保存条件 Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
说明 This product is for research use only.
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