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| 产品编号 | KMH310 |
|---|---|
| 产品名称 | Recombinant Human CD134/TNFRSF4 Protein, His Tag |
| 产品描述 | Recombinant Human CD134/TNFRSF4 Protein, His Tag (KMH310) contains the human TNFRSF4(Met1-Ala216) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
| 分子名称 | TNFRSF4 |
| 产品别称 | OX40, ACT35, CD134, IMD16, TXGP1L, TNF receptor superfamily member 4 |
| 规格 | 50ug, 100ug |
| 物种 | Human |
| 宿主 | Mammalian cells |
| 蛋白家族 | CD molecule |
| 编录号 | P43489 |
| 纯度 | ≥90% as determined by SDS-PAGE |
| 内毒素水平 | < 1.0 EU per ug of the protein as determined by the LAL method. |
| 缓冲体系 | PBS |
| 分子量 | 23.76 kDa |
| 纯化方式 | Affinity Purification |
| 产品背景 | OX4L, a member of the TNF superfamily of structurally related proteins, exists primarily as a type II membrane bound, non-covalently linked homotrimeric protein. It is expressed on antigen presenting cells (APCs), such as dendritic cells and activated B-cells, and also on various other cells such as vascular endothelial cells, mast cells, and natural killer cells. OX4L signals specifically through the OX4 receptor, which is expressed predominantly on CD4+T cells but also on certain activated CD8+T cells. OX4/OX4L functions as a costimulatory signal, which is required for a productive interaction between antigen presenting cells and their target T-cells. It enhances cell proliferation and survival, and increases expression of RANTES, IL-2, IL-3, and IFN&gamma. |
| 保存条件 | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
