EBOV (subtype Zaire, strain Mayinga 1976) GP Protein, His Tag
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产品编号
KMP4439
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别名
埃博拉病毒包膜糖蛋白, EBOV GP, Glycoprotein, EBOV GP Protein
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规格
- 50ug
- 100ug
- 200ug
产品介绍
| Alias | 埃博拉病毒包膜糖蛋白, EBOV GP, Glycoprotein, EBOV GP Protein |
| Catalog Number | KMP4439 |
| Product Description | The EBOV (subtype Zaire, strain Mayinga 1976) GP Protein(KMP4439) is produced in HEK293 Cells. A DNA sequence encoding the Zaire ebolavirus (strain Mayinga 1976) GP (AAC54887.1) (Met1-Phe308) was expressed with a polyhistidine tag at the C-terminus. |
| Molecular Name | EBOV GP |
| Species | EBOV |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Purity | >95% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | 50mM Tris, 500mM NaCl |
| Background | HCV NS3 displays three enzymatic activities: serine protease, NTPase, and RNA helicase. HCV NS3 serine protease, in association with NS4A, is responsible for the cleavages of NS3-NS4A, NS4A-NS4B, NS4B-NS5A, and NS5A-NS5B. HCV NS3 RNA helicase binds to RNA and unwinds dsRNA in the 3' to 5' direction, and likely RNA stable secondary structure in the template strand (By similarity). Cleaves and inhibits the host antiviral protein MAVS. NS3/NS4A complex also prevents phosphorylation of human IRF3, thus preventing the establishment of dsRNA induced antiviral state. One of the HCV proteases, NS3-4A serine protease, is a non-covalent heterodimer consisting of a catalytic subunit (the N-terminal one-third of NS3 protein) and an activating cofactor (NS4A protein) and is responsible for cleavage at four sites of the HCV polyprotein. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
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