DENV (type 4, strain Philippines/H241/1956) NS1 Protein, His Tag
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产品编号
KMP4427
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别名
登革热病毒糖蛋白NS1, DENV NS1, Nonstructural Protein 1, DENV NS1 Protein
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规格
- 50ug
- 100ug
- 200ug
Alias | 登革热病毒糖蛋白NS1, DENV NS1, Nonstructural Protein 1, DENV NS1 Protein |
Catalog Number | KMP4427 |
Product Description | The DENV (type 4, strain Philippines/H241/1956) NS1 Protein(KMP4427) is produced in HEK293 Cells. A DNA sequence encoding the Dengue virus (DENV) (type 4, strain Philippines/H241/1956) NS1 (AAX48017.1 (aa775-1126)) (Asp1-Ala352) was expressed with a polyhistidine tag at the N-terminus. |
Molecular Name | DENV NS1 |
Species | DENV |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >90% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | Envelope of Zika virus is responsible for receptor binding and membrane. Analysis of the envelope protein of Zika, from Brazilian Zika SPH215 (KU321639), indicates predicted B and T cell epitopes in peptides that are consistent with those reported for dengue, YFYF and Japanese encephalitis. The envelope Domain II B cell epitope, to which much dengue non-neutralizing cross-reaction is attributed, is also conserved also in Zika virus, consistent with prior field observations of cross-reactivity with dengue and YF. Domain III of the Zika envelope protein, likely the main specific neutralizing domain, is distinct from recent Brazilian dengue isolates and a recent Peruvian YF isolate (GQ379163), 76% of possible major histocompatibility complex class (MHC) I and MHC II binding peptides and potential B cell linear epitopes are unique to Zika virus. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |