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Rabbit Anti Human BNP Polyclonal Antibody

Rabbit Anti Human BNP Polyclonal Antibody

产品编号

PA12838

别名

BNP antibody, BNP polyclonal antibody, BNP Rabbit pAb, BNP, Iso-ANP

规格
  • 50ul
  • 100ul
  • 200ul
产品介绍
AliasBNP antibody, BNP polyclonal antibody, BNP Rabbit pAb, BNP, Iso-ANP
Catalog NumberPA12838
Product DescriptionThe Rabbit Anti Human BNP Polyclonal Antibody was obtained by affinity purification from a rabbit immunized with a purified synthetic peptide corresponding to a sequence within amino acids 35-134 of human BNP (NP_002512.1)
HostRabbit
Size50ul, 100ul, 200ul
ClonityPolyclonal
PurificationAffinity purification
FormulationBuffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
BackgroundThis gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The presence of myocardial injury is a significant predictor of mortality in hospitalized coronavirus disease 2019 (COVID-19) patients, and there is evidence of increased levels of natriuretic peptide B in hospitalized non-survivor COVID-19 patients. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis.
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 35-134 of human BNP (NP_002512.1)
Storage ConditionStore at -20℃. Avoid freeze / thaw cycles.
Shipping ConditionThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stabilitystable at -20 ° C
Cross-reactivityHuman, Mouse, Rat
Product Declaration本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
FAQ
  • Q1- 是否用于心力衰竭诊断?

    是,检测血浆B型利钠肽(BNP),ELISA灵敏度0.5 pg/mL,符合CLIA标准。

  • Q2- 是否与ANP(心房利钠肽)交叉反应?

    交叉反应率<0.1%,确保BNP特异性检测。

  • Q3- 样本类型及处理?

    EDTA抗凝血浆,4℃离心(3000 rpm,10分钟)去除血小板。

  • Q4- 是否支持化学发光法?

    是,检测限0.1 pg/mL,动态范围1-5000 pg/mL(适配Roche Cobas平台)。

  • Q5- 保存条件?

    冻干粉-80℃保存3年,复溶后4℃保存1周(含0.1% BSA)。

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